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Molecular organization of C9 within the membrane attack complex of complement. Induction of circular C9 polymerization by the C5b-8 assembly

Evidence has been presented suggesting that during assembly of the membrane attack complex (MAC) of complement, the C5b-8 complex induces polymerization of C9. The C9 polymer was detected by sodium dodecyl sulfate (SDS) gel electrophoresis of MAC isolated from complement-lysed erythrocytes. It resem...

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Detalhes bibliográficos
Main Authors: Podack, ER, Tschoop, J, Muller-Eberhard, HJ
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186720/
https://ncbi.nlm.nih.gov/pubmed/6177822
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