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Assembly of the functional membrane attack complex of human complement: formation of disulfide-linked C9 dimers.

The 158,000 Mr protein, previously designated C5c, present in fully assembled complement (C) membrane attack complexes (MC5b-9) has been identified as a disulfide-bonded dimer of C9. This conclusion was based on the observations that: (i) a portion of the 125I-radiolabeled precursor C9 incorporated...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ware, C F, Kolb, W P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6796960/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.10.6426
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