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Polymerization of the ninth component of complement (C9): formation of poly(C9) with a tubular ultrastructure resembling the membrane attack complex of complement.

The ninth component of complement (C9) has a marked propensity to polymerize. C9 polymers [poly(C9)] formed spontaneously in Veronal-buffered saline upon incubation of purified C9 for 64 hr at 37 degrees C or within 2 hr at 46--56 degrees C. Poly(C9) formed at 37 degrees C was visualized by electron...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Podack, E R, Tschopp, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6952208/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.2.574
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