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Emetine Regulates the Alternative Splicing of Bcl-x Through Protein Phosphatase-1 Dependent Mechanism
Exon 2 of the Bcl-x gene undergoes alternative splicing in which the Bcl-xS splice variant promotes apoptosis in contrast to the anti-apoptotic splice variants, Bcl-xL. In this study, the regulation of the alternative splicing of pre-mRNA of Bcl-x was examined in response to emetine. Treatment of di...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2186211/ https://ncbi.nlm.nih.gov/pubmed/18096507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.11.004 |
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