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Emetine regulates the alternative splicing of caspase 9 in tumor cells

Exons 3 to 6 in the caspase 9 gene undergo alternative splicing in which the larger caspase 9 splice variant promotes apoptosis, in contrast to the dominant negative anti-apoptotic splice variant, the smaller caspase 9b. In this study, the regulation of the alternative splicing of caspase 9 pre-mRNA...

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Detalhes bibliográficos
Main Authors: PAN, DANMIN, BOON-UNGE, KRITSANAPOL, GOVITRAPONG, PIYARAT, ZHOU, JIANHUA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406502/
https://ncbi.nlm.nih.gov/pubmed/22848307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.395
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