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Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice

In young adulthood, MRL/Mp-lpr/lpr mice develop severe systemic lupus erythematosus (SLE)-like syndrome associated with massive T cell proliferation. The congenic MRL/Mp- mice lack the lpr gene and develop chronic SLE late in life. We have exchanged thymic transplants between these substrains so as...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186176/
https://ncbi.nlm.nih.gov/pubmed/6972998
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