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Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin

We report an intracellular peptide delivery system capable of targeting specific cellular compartments. In the model system we constructed a chimeric protein consisting of the nontoxic B subunit of Escherichia coli heat-labile enterotoxin (EtxB) fused to a 27-mer peptide derived from the DNA polymer...

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Autors principals: Loregian, Arianna, Papini, Emanuele, Satin, Barbara, Marsden, Howard S., Hirst, Timothy R., Palù, Giorgio
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21845/
https://ncbi.nlm.nih.gov/pubmed/10220447
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