Protective Mucosal Immunity to Ocular Herpes Simplex Virus Type 1 Infection in Mice by Using Escherichia coli Heat-Labile Enterotoxin B Subunit as an Adjuvant

The potential of nontoxic recombinant B subunits of cholera toxin (rCtxB) and its close relative Escherichia coli heat-labile enterotoxin (rEtxB) to act as mucosal adjuvants for intranasal immunization with herpes simplex virus type 1 (HSV-1) glycoproteins was assessed. Doses of 10 μg of rEtxB or ab...

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Autori principali: Richards, C. M., Aman, A. T., Hirst, T. R., Hill, T. J., Williams, N. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114075/
https://ncbi.nlm.nih.gov/pubmed/11160664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.4.1664-1671.2001
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