Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin

We report an intracellular peptide delivery system capable of targeting specific cellular compartments. In the model system we constructed a chimeric protein consisting of the nontoxic B subunit of Escherichia coli heat-labile enterotoxin (EtxB) fused to a 27-mer peptide derived from the DNA polymer...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Loregian, Arianna, Papini, Emanuele, Satin, Barbara, Marsden, Howard S., Hirst, Timothy R., Palù, Giorgio
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21845/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220447/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5221
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