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Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease
The cyclobutane thymine dimer is the major DNA lesion induced in human skin by sunlight and is a primary cause of skin cancer, the most prevalent form of cancer in the Northern Hemisphere. In humans, the only known cellular repair mechanism for eliminating the dimer from DNA is nucleotide excision r...
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| Päätekijät: | , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cold Spring Harbor Laboratory Press
2003
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC218148/ https://ncbi.nlm.nih.gov/pubmed/14522951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1131003 |
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