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Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease

The cyclobutane thymine dimer is the major DNA lesion induced in human skin by sunlight and is a primary cause of skin cancer, the most prevalent form of cancer in the Northern Hemisphere. In humans, the only known cellular repair mechanism for eliminating the dimer from DNA is nucleotide excision r...

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Detalles Bibliográficos
Publicado en:Genes Dev
Principais autores: Reardon, Joyce T., Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218148/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14522951/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1131003
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