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Energy metabolism and T-cell-mediated cytolysis. II. Selective inhibition of cytolysis by 2-deoxy-D-glucose

The effect of the hexose analogue 2-deoxy-D-glucose (2-DG) on T-cell- mediated cytolysis has been investigated. 2-DG inhibited cytolysis in glucose-free medium but not in medium containing equimolar concentrations of glucose. This inhibition was reversible and quantitatively competitive with glucose...

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Dettagli Bibliografici
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1977
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180795/
https://ncbi.nlm.nih.gov/pubmed/302305
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