Lysine-Specific Demethylase 1 (LSD1) Is Required for the Transcriptional Repression of the Telomerase Reverse Transcriptase (hTERT) Gene

BACKGROUND: Lysine-specific demethylase 1 (LSD1), catalysing demethylation of mono- and di-methylated histone H3-K4 or K9, exhibits diverse transcriptional activities by mediating chromatin reconfiguration. The telomerase reverse transcriptase (hTERT) gene, encoding an essential component for telome...

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Detalhes bibliográficos
Main Authors: Zhu, Qingjun, Liu, Cheng, Ge, Zheng, Fang, Xiaolei, Zhang, Xi, Strååt, Klas, Björkholm, Magnus, Xu, Dawei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180196/
https://ncbi.nlm.nih.gov/pubmed/18197256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001446
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