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Suppression of telomerase reverse transcriptase (hTERT) expression in differentiated HL-60 cells: regulatory mechanisms

Telomerase activity, associated with cellular immortalization and tumorigenesis, is suppressed during terminal differentiation of HL-60 promyelocytic leukaemic cells. However, it is poorly understood how telomerase activity is regulated in differentiated HL-60 cells. In the present study, we demonst...

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Detalhes bibliográficos
Main Authors: Xu, D, Gruber, A, Björkholm, M, Peterson, C, Pisa, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362380/
https://ncbi.nlm.nih.gov/pubmed/10376966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690480
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