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G protein βγ subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)

Ras-GRF1 has been implicated as a Ras-specific guanine nucleotide exchange factor (GEF), which mediates calcium- and muscarinic receptor-triggered signals in the brain. Although a Dbl homology domain known as a motif conserved among GEFs that target Rho family GTP-binding proteins exists in Ras-GRF1...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kiyono, Mari, Satoh, Takaya, Kaziro, Yoshito
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220378/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.4826
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