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G protein βγ subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)

Ras-GRF1 has been implicated as a Ras-specific guanine nucleotide exchange factor (GEF), which mediates calcium- and muscarinic receptor-triggered signals in the brain. Although a Dbl homology domain known as a motif conserved among GEFs that target Rho family GTP-binding proteins exists in Ras-GRF1...

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Hlavní autoři: Kiyono, Mari, Satoh, Takaya, Kaziro, Yoshito
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC21776/
https://ncbi.nlm.nih.gov/pubmed/10220378
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