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Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells

Primary biliary cirrhosis (PBC) is a cholestatic disease associated with autoimmune phenomena and alterations in both biliary bicarbonate excretion and expression of the bicarbonate carrier AE2. The bile acid ursodeoxycholic acid (UCDA) is currently used in treatment of cholestatic liver diseases an...

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Autori principali: Arenas, Fabián, Hervias, Isabel, Úriz, Miriam, Joplin, Ruth, Prieto, Jesús, Medina, Juan F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176189/
https://ncbi.nlm.nih.gov/pubmed/18188457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33156
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