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Promoter hypermethylation of the AE2/SLC4A2 gene in PBC
BACKGROUND & AIMS: Patients with primary biliary cholangitis (PBC) exhibit reduced AE2/SLC4A2 gene expression in the liver and peripheral blood mononuclear cells (PBMCs). AE2 encodes a Cl(–)/HCO(3)(–) exchanger involved in biliary bicarbonate secretion and intracellular pH regulation. Reduced AE...
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| 出版年: | JHEP Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7001545/ https://ncbi.nlm.nih.gov/pubmed/32039364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2019.05.006 |
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