Ursodeoxycholic Acid Inhibits Hepatic Cystogenesis in Experimental Models of Polycystic Liver Disease

BACKGROUND & AIMS: Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive biliary cystogenesis. Current therapies show short-term and/or modest beneficial effects. Cystic cholangiocytes hyperproliferate as a consequence of diminished intracellular calcium levels ([Ca...

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Bibliografske podrobnosti
izdano v:J Hepatol
Main Authors: Munoz-Garrido, Patricia, Marin, Jose J. G., Perugorria, María J., Urribarri, Aura D., Erice, Oihane, Sáez, Elena, Uriz, Miriam, Sarvide, Sarai, Portu, Ainhoa, Concepcion, Axel R., Romero, Marta R., Monte, Maria J., Santos-Laso, Alvaro, Hijona, Elizabeth, Jimenez-Agüero, Raul, Marzioni, Marco, Beuers, Ulrich, Masyuk, Tatyana V., LaRusso, Nicholas F., Prieto, Jesús, Bujanda, Luis, Drenth, Joost P.H., Banales, Jesús M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575914/
https://ncbi.nlm.nih.gov/pubmed/26044126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.05.023
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