Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia

The Plasmodium falciparum variant erythrocyte surface antigens known as PfEMP1, encoded by the var gene family, are thought to play a crucial role in malaria pathogenesis because they mediate adhesion to host cells and immuno-modulation. Var genes have been divided into three major groups (A, B and...

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Hauptverfasser: Kyriacou, Helen M., Stone, Graham N., Challis, Richard J., Raza, Ahmed, Lyke, Kirsten E., Thera, Mahamadou A., Koné, Abdoulaye K., Doumbo, Ogobara K., Plowe, Christopher V., Rowe, J. Alexandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier/North-Holland Biomedical Press 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176080/
https://ncbi.nlm.nih.gov/pubmed/16996149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2006.08.005
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