Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia

The Plasmodium falciparum variant erythrocyte surface antigens known as PfEMP1, encoded by the var gene family, are thought to play a crucial role in malaria pathogenesis because they mediate adhesion to host cells and immuno-modulation. Var genes have been divided into three major groups (A, B and...

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Main Authors: Kyriacou, Helen M., Stone, Graham N., Challis, Richard J., Raza, Ahmed, Lyke, Kirsten E., Thera, Mahamadou A., Koné, Abdoulaye K., Doumbo, Ogobara K., Plowe, Christopher V., Rowe, J. Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier/North-Holland Biomedical Press 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176080/
https://ncbi.nlm.nih.gov/pubmed/16996149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2006.08.005
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