Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting

Malaria has been a major selective force on the human population, and several erythrocyte polymorphisms have evolved that confer resistance to severe malaria. Plasmodium falciparum rosetting, a parasite virulence phenotype associated with severe malaria, is reduced in blood group O erythrocytes comp...

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Detalhes bibliográficos
Main Authors: Rowe, J. Alexandra, Handel, Ian G., Thera, Mahamadou A., Deans, Anne-Marie, Lyke, Kirsten E., Koné, Abdoulaye, Diallo, Dapa A., Raza, Ahmed, Kai, Oscar, Marsh, Kevin, Plowe, Christopher V., Doumbo, Ogobara K., Moulds, Joann M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077280/
https://ncbi.nlm.nih.gov/pubmed/17959777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705390104
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