Effects of the central analgesic tramadol and its main metabolite, O-desmethyltramadol, on rat locus coeruleus neurones.

1. Tramadol is a centrally acting analgesic with low opioid receptor affinity and, therefore, presumably additional mechanisms of analgesic action. Tramadol and its main metabolite O-desmethyltramadol were tested on rat central noradrenergic neurones of the nucleus locus coeruleus (LC), which are in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sevcik, J., Nieber, K., Driessen, B., Illes, P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1993
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175982/
https://ncbi.nlm.nih.gov/pubmed/8220877
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