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The diuretic action of 8-cyclopentyl-1,3-dipropylxanthine, a selective A1 adenosine receptor antagonist.

1. The diuretic effect of the selective A1 adenosine receptor antagonist, 8-cyclopentyl-1,3-dipropylxanthine (CPX), was investigated in anaesthetized rats. 2. CPX (0.1 mg kg-1, i.v.) produced significant increases in urine flow, and the excretion rate and fractional excretion of both sodium and chlo...

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Bibliographic Details
Main Authors: Knight, R. J., Bowmer, C. J., Yates, M. S.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175587/
https://ncbi.nlm.nih.gov/pubmed/8495243
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