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Effects of N(6)-cyclopentyl adenosine and 8-cyclopentyl-l,3-dipropylxanthine on N-methyl-d-aspartate induced seizures in mice

The effect of the adenosine A(1) receptor agonist N(6)-cyclopentyladenosine (CPA) and antagonist 8-cyclopentyl-l,3-dipropylxanthine (CPX) on N-methyl-d-aspartate (NMDA)-evoked seizures was studied in C57BL/6 mice (20/group). Animals were injected i.p. either with CPA (0.5, 1, 2 mg/kg) or CPX (1, 2 m...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Von Lubitz, Dag K.J.E., Paul, Ian A., Carter, Margaret, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531604/
https://ncbi.nlm.nih.gov/pubmed/8287913
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