A non-peptide NK1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically.

1. The non-peptide neurokinin NK1-receptor antagonist, RP 67580 (3aR, 7aR), a perhydroisoindolone derivative, powerfully reduced plasma extravasation in rat hind paw skin induced by local application of xylene (ID50 = 0.03 mg kg-1, i.v.) or capsaicin (ID50 = 0.06 mg kg-1, i.v.), or by i.v. injection...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Moussaoui, S. M., Montier, F., Carruette, A., Blanchard, J. C., Laduron, P. M., Garret, C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175579/
https://ncbi.nlm.nih.gov/pubmed/7684305
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki