Pitfalls in the Denaturing High-Performance Liquid Chromatography Analysis of Mitochondrial DNA Mutation

Denaturing high-performance liquid chromatography (DHPLC) purification of heteroduplexes has been reported as a method to increase sensitivity of the detection of low-level heteroplasmy by DNA sequencing, and DHPLC profiling has been suggested as a method to allow the correlation of a characteristic...

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Библиографические подробности
Главные авторы: Lim, Kok Seong, Naviaux, Robert K., Wong, Scott, Haas, Richard H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2008
Предметы:
Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175549/
https://ncbi.nlm.nih.gov/pubmed/18165269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2008.070081
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