Systemic Mastocytosis Associated with Chronic Idiopathic Myelofibrosis: A Distinct Subtype of Systemic Mastocytosis-Associated Clonal Hematological Nonmast Cell Lineage Disorder Carrying the Activating Point Mutations KIT(D816V) and JAK2(V617F)

In ∼20 to 30% of patients with systemic mastocytosis (SM), an associated clonal hematological nonmast cell lineage disorder (AHNMD) is diagnosed. Although SM may be considered to be closely related to the myeloproliferative disorders (MPDs), it is unknown whether JAK2(V617F+) MPD may occur as AHNMD...

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Autors principals: Sotlar, Karl, Bache, Anja, Stellmacher, Florian, Bültmann, Burkhard, Valent, Peter, Horny, Hans-Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2008
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175544/
https://ncbi.nlm.nih.gov/pubmed/18165278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2008.070061
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