Adverse Prognostic Impact of the KIT D816V Transcriptional Activity in Advanced Systemic Mastocytosis

In systemic mastocytosis (SM), qualitative and serial quantitative assessment of the KIT D816V mutation is of diagnostic and prognostic relevance. We investigated peripheral blood and bone marrow samples of 161 patients (indolent SM (ISM), n = 40; advanced SM, AdvSM, n = 121) at referral and during...

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Publicado en:Int J Mol Sci
Autores principales: Naumann, Nicole, Lübke, Johannes, Baumann, Sofie, Schwaab, Juliana, Hoffmann, Oliver, Kreil, Sebastian, Dangelo, Vito, Reiter, Lukas, Bugert, Peter, Kristensen, Thomas, Sotlar, Karl, Haselmann, Verena, Schneider, Sven, Metzgeroth, Georgia, Weiss, Christel, Popp, Henning D., Fabarius, Alice, Hofmann, Wolf-Karsten, Cross, Nicholas C. P., Reiter, Andreas, Jawhar, Mohamad
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961551/
https://ncbi.nlm.nih.gov/pubmed/33806359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052562
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