Beyond Parkinson Disease: Amyotrophic Lateral Sclerosis and the Axon Guidance Pathway

BACKGROUND: We recently described a genomic pathway approach to study complex diseases. We demonstrated that models constructed using single nucleotide polymorphisms (SNPs) within axon guidance pathway genes were highly predictive of Parkinson disease (PD) susceptibility, survival free of PD, and ag...

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Autors principals: Lesnick, Timothy G., Sorenson, Eric J., Ahlskog, J. Eric, Henley, John R., Shehadeh, Lina, Papapetropoulos, Spiridon, Maraganore, Demetrius M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175528/
https://ncbi.nlm.nih.gov/pubmed/18197259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001449
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