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Beyond Parkinson Disease: Amyotrophic Lateral Sclerosis and the Axon Guidance Pathway

BACKGROUND: We recently described a genomic pathway approach to study complex diseases. We demonstrated that models constructed using single nucleotide polymorphisms (SNPs) within axon guidance pathway genes were highly predictive of Parkinson disease (PD) susceptibility, survival free of PD, and ag...

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Detalhes bibliográficos
Main Authors: Lesnick, Timothy G., Sorenson, Eric J., Ahlskog, J. Eric, Henley, John R., Shehadeh, Lina, Papapetropoulos, Spiridon, Maraganore, Demetrius M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175528/
https://ncbi.nlm.nih.gov/pubmed/18197259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001449
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