Beyond Parkinson Disease: Amyotrophic Lateral Sclerosis and the Axon Guidance Pathway

BACKGROUND: We recently described a genomic pathway approach to study complex diseases. We demonstrated that models constructed using single nucleotide polymorphisms (SNPs) within axon guidance pathway genes were highly predictive of Parkinson disease (PD) susceptibility, survival free of PD, and ag...

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Главные авторы: Lesnick, Timothy G., Sorenson, Eric J., Ahlskog, J. Eric, Henley, John R., Shehadeh, Lina, Papapetropoulos, Spiridon, Maraganore, Demetrius M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2008
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175528/
https://ncbi.nlm.nih.gov/pubmed/18197259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001449
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