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TAK1 MAPKKK mediates TGF-β signaling by targeting SnoN oncoprotein for degradation
Transforming growth factor-β (TGF-β) regulates a variety of physiologic processes through essential intracellular mediators Smads. The SnoN oncoprotein is an inhibitor of TGF-β signaling. SnoN recruits transcriptional repressor complex to block Smad-dependent transcriptional activation of TGF-β-resp...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175395/ https://ncbi.nlm.nih.gov/pubmed/17276978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700875200 |
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