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Real-time measurements of the nucleation, growth and dissociation of single Rad51–DNA nucleoprotein filaments

Human Rad51 (hRad51), the protein central to DNA pairing and strand exchange during homologous recombination, polymerizes on DNA to form nucleoprotein filaments. By making use of magnetic tweezers to manipulate individual DNA molecules, we measured the nucleation and growth of hRad51 nucleoprotein f...

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Bibliographic Details
Main Authors: Miné, Judith, Disseau, Ludovic, Takahashi, Masayuki, Cappello, Giovanni, Dutreix, Marie, Viovy, Jean-Louis
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175369/
https://ncbi.nlm.nih.gov/pubmed/17947332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm752
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