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Direct observation of twisting steps during Rad51 polymerization on DNA
The human recombinase hRad51 is a key protein for the maintenance of genome integrity and for cancer development. Polymerization and depolymerization of hRad51 on duplex DNA were studied here using a new generation of magnetic tweezers, measuring DNA twist in real time with a resolution of 5°. Our r...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2780809/ https://ncbi.nlm.nih.gov/pubmed/19884492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902234106 |
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