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Structural and torsional properties of the RAD51-dsDNA nucleoprotein filament

Human RAD51 is a key protein in the repair of DNA by homologous recombination. Its assembly onto DNA, which induces changes in DNA structure, results in the formation of a nucleoprotein filament that forms the basis of strand exchange. Here, we determine the structural and mechanical properties of R...

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Detalhes bibliográficos
Main Authors: Lee, Mina, Lipfert, Jan, Sanchez, Humberto, Wyman, Claire, Dekker, Nynke H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737536/
https://ncbi.nlm.nih.gov/pubmed/23703213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt425
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