The Ser(176) of T4 endonuclease IV is crucial for the restricted and polarized dC-specific cleavage of single-stranded DNA implicated in restriction of dC-containing DNA in host Escherichia coli

Endonuclease (Endo) IV encoded by denB of bacteriophage T4 is an enzyme that cleaves single-stranded (ss) DNA in a dC-specific manner. Also the growth of dC-substituted T4 phage and host Escherichia coli cells is inhibited by denB expression presumably because of the inhibitory effect on replication...

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Bibliographic Details
Main Authors: Hirano, Nobutaka, Ohshima, Hiroyuki, Sakashita, Hidenori, Takahashi, Hideo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175332/
https://ncbi.nlm.nih.gov/pubmed/17913749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm722
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