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Modeling DNA-binding of Escherichia coli σ(70) exhibits a characteristic energy landscape around strong promoters
We present a computational model of DNA-binding by σ(70) in Escherichia coli which allows us to extract the functional characteristics of the wider promoter environment. Our model is based on a measure for the binding energy of σ(70) to the DNA, which is derived from promoter strength data and used...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175306/ https://ncbi.nlm.nih.gov/pubmed/17940097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm720 |
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