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Membrane Topogenesis of a Type I Signal-Anchor Protein, Mouse Synaptotagmin Ii, on the Endoplasmic Reticulum

Synaptotagmin II is a type I signal-anchor protein, in which the NH(2)-terminal domain of 60 residues (N-domain) is located within the lumenal space of the membrane and the following hydrophobic region (H-region) shows transmembrane topology. We explored the early steps of cotranslational integratio...

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Detalhes bibliográficos
Main Authors: Kida, Yuichiro, Sakaguchi, Masao, Fukuda, Mitsunori, Mikoshiba, Katsuhiko, Mihara, Katsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175286/
https://ncbi.nlm.nih.gov/pubmed/10952998
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