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Translocation of a long amino-terminal domain through ER membrane by following signal-anchor sequence

Type I signal-anchor sequences mediate translocation of the N-terminal domain (N-domain) across the endoplasmic reticulum (ER) membrane. To examine the translocation in detail, dihydrofolate reductase (DHFR) was fused to the N-terminus of synaptotagmin II as a long N-domain. Translocation was arrest...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kida, Yuichiro, Mihara, Katsuyoshi, Sakaguchi, Masao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224678/
https://ncbi.nlm.nih.gov/pubmed/16107879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600788
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