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Translocation of a long amino-terminal domain through ER membrane by following signal-anchor sequence
Type I signal-anchor sequences mediate translocation of the N-terminal domain (N-domain) across the endoplasmic reticulum (ER) membrane. To examine the translocation in detail, dihydrofolate reductase (DHFR) was fused to the N-terminus of synaptotagmin II as a long N-domain. Translocation was arrest...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224678/ https://ncbi.nlm.nih.gov/pubmed/16107879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600788 |
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