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Systems metabolic engineering of Escherichia coli for L-threonine production

Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by...

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Autori principali: Lee, Kwang Ho, Park, Jin Hwan, Kim, Tae Yong, Kim, Hyun Uk, Lee, Sang Yup
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174629/
https://ncbi.nlm.nih.gov/pubmed/18059444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100196
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