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Metabolic Engineering of Escherichia coli for Enhanced Production of Succinic Acid, Based on Genome Comparison and In Silico Gene Knockout Simulation

Comparative analysis of the genomes of mixed-acid-fermenting Escherichia coli and succinic acid-overproducing Mannheimia succiniciproducens was carried out to identify candidate genes to be manipulated for overproducing succinic acid in E. coli. This resulted in the identification of five genes or o...

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Sonraí Bibleagrafaíochta
Main Authors: Lee, Sang Jun, Lee, Dong-Yup, Kim, Tae Yong, Kim, Byung Hun, Lee, Jinwon, Lee, Sang Yup
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317394/
https://ncbi.nlm.nih.gov/pubmed/16332763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.12.7880-7887.2005
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