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Systems metabolic engineering of Escherichia coli for L-threonine production

Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by...

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Autors principals: Lee, Kwang Ho, Park, Jin Hwan, Kim, Tae Yong, Kim, Hyun Uk, Lee, Sang Yup
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174629/
https://ncbi.nlm.nih.gov/pubmed/18059444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100196
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