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Systems metabolic engineering of Escherichia coli for L-threonine production

Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by...

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Hlavní autoři: Lee, Kwang Ho, Park, Jin Hwan, Kim, Tae Yong, Kim, Hyun Uk, Lee, Sang Yup
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174629/
https://ncbi.nlm.nih.gov/pubmed/18059444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100196
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