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Systems metabolic engineering of Escherichia coli for L-threonine production
Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174629/ https://ncbi.nlm.nih.gov/pubmed/18059444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100196 |
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