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Systems metabolic engineering of Escherichia coli for L-threonine production

Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Kwang Ho, Park, Jin Hwan, Kim, Tae Yong, Kim, Hyun Uk, Lee, Sang Yup
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174629/
https://ncbi.nlm.nih.gov/pubmed/18059444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100196
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