Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides

BACKGROUND: A right-handed, calcium-dependent β-roll structure found in secreted proteases and repeat-in-toxin proteins was used as a template for the design of minimal, soluble, monomeric polypeptides that would fold in the presence of Ca(2+). Two polypeptides were synthesised to contain two and fo...

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Bibliografiska uppgifter
Huvudupphovsmän: Scotter, Andrew J, Guo, Meng, Tomczak, Melanie M, Daley, Margaret E, Campbell, Robert L, Oko, Richard J, Bateman, David A, Chakrabartty, Avijit, Sykes, Brian D, Davies, Peter L
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2007
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174480/
https://ncbi.nlm.nih.gov/pubmed/17908326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-63
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