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Dock ’n Roll: Folding of a Silk-Inspired Polypeptide into an Amyloid-like Beta Solenoid

Polypeptides containing the motif ((GA)(m)GX)(n) occur in silk (we refer to them as ‘silk-like’) and have a strong tendency to self-assemble. For example, polypeptides containing (GAGAGAGX)(n), where X = G or H have been observed to form filaments; similar sequences but with X = Q have been used in...

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Publié dans:Soft Matter
Auteurs principaux: Zhao, Binwu, Cohen Stuart, Martien A., Hall, Carol K.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913789/
https://ncbi.nlm.nih.gov/pubmed/26947809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sm00169f
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