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Navigating in foldonia: Using accelerated molecular dynamics to explore stability, unfolding and self-healing of the β-solenoid structure formed by a silk-like polypeptide

The β roll molecules with sequence (GAGAGAGQ)(10) stack via hydrogen bonding to form fibrils which have been themselves been used to make viral capsids of DNA strands, supramolecular nanotapes and pH-responsive gels. Accelerated molecular dynamics (aMD) simulations are used to investigate the unfold...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Zhao, Binwu, Cohen Stuart, Martien A., Hall, Carol K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388506/
https://ncbi.nlm.nih.gov/pubmed/28329017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005446
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