In Utero Exposure to Di(n-butyl) Phthalate and Testicular Dysgenesis: Comparison of Fetal and Adult End Points and Their Dose Sensitivity

BACKGROUND: Fetal exposure of male rats to di(n-butyl) phthalate (DBP) induces reproductive disorders similar to those in human testicular dysgenesis syndrome (TDS), including infertility, cryptorchidism, focal “dysgenetic areas,” and Sertoli cell–only tubules in the adult testis. Humans are widely...

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Autori principali: Mahood, I. Kim, Scott, Hayley M., Brown, Richard, Hallmark, Nina, Walker, Marion, Sharpe, Richard M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Institute of Environmental Health Sciences 2007
Soggetti:
Monograph
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174411/
https://ncbi.nlm.nih.gov/pubmed/18174951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9366
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