Effects of Monobutyl and Di(n-butyl) Phthalate in Vitro on Steroidogenesis and Leydig Cell Aggregation in Fetal Testis Explants from the Rat: Comparison with Effects in Vivo in the Fetal Rat and Neonatal Marmoset and in Vitro in the Human

BACKGROUND: Certain phthalates can impair Leydig cell distribution and steroidogenesis in the fetal rat in utero, but it is unknown whether similar effects might occur in the human. OBJECTIVES: Our aim in this study was to investigate the effects of di(n-butyl) phthalate (DBP), or its metabolite mon...

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Detalhes bibliográficos
Main Authors: Hallmark, Nina, Walker, Marion, McKinnell, Chris, Mahood, I. Kim, Scott, Hayley, Bayne, Rosemary, Coutts, Shiona, Anderson, Richard A., Greig, Irene, Morris, Keith, Sharpe, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1849934/
https://ncbi.nlm.nih.gov/pubmed/17431488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9490
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