Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells

BACKGROUND: Etomidate is a rapid hypnotic intravenous anesthetic agent. The major side effect of etomidate is the reduced plasma concentration of corticosteroids, leading to the abnormal reaction of adrenals. Cortisol and testosterone biosynthesis has similar biosynthetic pathway, and shares several...

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Udgivet i:PLoS One
Main Authors: Liu, Hua-Cheng, Zhu, Danyan, Wang, Chan, Guan, Hongguo, Li, Senlin, Hu, Cong, Chen, Zhichuan, Hu, Yuanyuan, Lin, Han, Lian, Qing-Quan, Ge, Ren-Shan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640886/
https://ncbi.nlm.nih.gov/pubmed/26555702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139311
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