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Caspases Disrupt the Nuclear-Cytoplasmic Barrier

During apoptosis, caspases, a family of proteases, disassemble a cell by cleaving a set of proteins. Caspase-3 plays a major role in the disassembly of the nucleus by processing several nuclear substrates. The question is how caspase-3, which is usually cytoplasmic, gains access to its nuclear targe...

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Detalhes bibliográficos
Main Authors: Faleiro, Lavina, Lazebnik, Yuri
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174353/
https://ncbi.nlm.nih.gov/pubmed/11085998
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