Constitutive nuclear localization and initial cytoplasmic apoptotic activation of endogenous caspase-3 evidenced by confocal microscopy

The localization of caspases and their substrates in different cellular compartments may be one way to regulate apoptosis. Caspase-3-dependent proteolysis of inhibitor caspase-activated deoxyribonuclease (ICAD) activates caspase-activated deoxyribonuclease (CAD), which induces apoptotic internucleos...

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Autores principales: Ramuz, Olivier, Isnardon, Daniel, Devilard, Elisabeth, Charafe-Jauffret, Emmanuelle, Hassoun, Jacques, Birg, Françoise, Xerri, Luc
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2003
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517548/
https://ncbi.nlm.nih.gov/pubmed/12801281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.2003.00339.x
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